NAD+

Description

Compound Specifications

Full name	Nicotinamide adenine dinucleotide
Compound class	Dinucleotide coenzyme — not a peptide
Molecular formula	C₂₁H₂₇N₇O₁₄P₂
Molecular weight	663.43 g/mol
CAS number	53-84-9
Structure	Two nucleotides joined by a phosphate bridge
Form	Lyophilized powder
Quantity	500mg per vial
Purity	≥99% (HPLC verified)
Storage (lyophilized)	2–8°C, protected from light and moisture
Storage (in solution)	2–8°C, use promptly — see handling notes
Third-party testing	Freedom Diagnostics

Verify molecular weight, formula and CAS against batch COA prior to publication.

What Distinguishes NAD+ From the Peptides in This Catalog

Every other compound Noxa Labs supplies is a peptide — a chain of amino acids linked by peptide bonds. NAD+ is not. It is a dinucleotide: two nucleotides, one containing an adenine base and the other a nicotinamide base, joined through a pair of bridging phosphate groups.

That structural difference has direct practical consequences for anyone handling it in a laboratory setting.

It is a redox-active molecule. NAD+ cycles between an oxidized form (NAD+) and a reduced form (NADH). This is the basis of its function as a coenzyme in cellular metabolism and it is why NAD+ is one of the most extensively characterized molecules in biochemistry — it appears in the literature not as a compound under investigation but as a fundamental component of the reactions being investigated.

It is markedly less stable in solution than a lyophilized peptide. The glycosidic bond is susceptible to hydrolysis, and degradation accelerates significantly at alkaline pH and at room temperature. Where a reconstituted peptide typically holds for 30 days refrigerated, NAD+ solutions have a considerably shorter useful window.

It is hygroscopic. The lyophilized powder readily absorbs atmospheric moisture, which initiates degradation before the vial is ever opened for use. Sealed storage matters more here than it does for the peptides in this catalog.

All statements above describe molecular and biochemical characteristics. No claim is made regarding outcomes of any kind in humans or animals.

Handling, Storage & Solution Preparation

Store the lyophilized powder at 2–8°C, sealed, protected from light and moisture. For extended storage, -20°C in a desiccated container is preferred. Allow the vial to reach room temperature before opening — opening a cold vial draws condensation onto hygroscopic powder.

Introduce bacteriostatic water slowly down the inner wall of the vial. Swirl gently until fully dissolved; do not shake. NAD+ dissolves readily and produces a clear, colorless to very faintly yellow solution. Pronounced yellow or brown coloration indicates degradation — discard the vial.

A 500mg vial reconstituted with 5mL of bacteriostatic water yields a 100mg/mL concentration.

Stability note: NAD+ in solution is not comparable to a reconstituted peptide. Keep refrigerated at all times, minimize time at room temperature, protect from light, and avoid alkaline conditions. Prepare solutions close to the point of use rather than storing them for extended periods.

Concentration and volume calculator →

Purity & Testing

Every batch is independently analyzed by Freedom Diagnostics before release. We publish HPLC purity data and endotoxin testing results — we don’t ask you to take our word for it. Certificates of Analysis are available for any lot; contact us with your order number.

View all Certificates of Analysis →

Frequently Asked Questions

Is NAD+ a peptide?
No. NAD+ is a dinucleotide coenzyme, not a chain of amino acids. It is a different class of molecule from every other compound in the Noxa Labs catalog and requires different handling.

What is the difference between NAD+ and NADH?
They are the oxidized and reduced forms of the same molecule. NAD+ is the oxidized form. The two interconvert through redox reactions.

Why does NAD+ need to be handled more carefully than peptides?
Two reasons. The lyophilized powder is hygroscopic and absorbs atmospheric moisture, and the molecule is substantially less stable in solution than a peptide — particularly at alkaline pH and at room temperature.

What does discoloration in the solution mean?
A clear, colorless to very faintly yellow solution is normal. Pronounced yellow or brown indicates degradation. Discard.

How is NAD+ different from NMN or NR?
NMN (nicotinamide mononucleotide) and NR (nicotinamide riboside) are precursor molecules in the NAD+ biosynthetic pathway. NAD+ is the coenzyme itself. Noxa Labs supplies NAD+.

What size is available?
500mg lyophilized vials.

Related Research Compounds

• MOTS-C — mitochondrial-derived peptide, encoded in mitochondrial DNA
• Certificates of Analysis — batch testing data

Research Use Only

For Research Use Only. This product is intended solely for laboratory research purposes. It is not a drug, food, dietary supplement, or cosmetic and may not be misbranded, misused, or mislabeled as such. Not for human or veterinary use. Not for diagnostic or therapeutic use. Not for resale without authorization.